簡要描述:Rabbit anti-TRPM2 Polyclonal Antibody Recombinant fusion protein containing a sequence corresponding to amino acids 1204-1503 of human TRPM2 (NP_003298.1).
Recombinant fusion protein containing a sequence corresponding to amino acids 1204-1503 of human TRPM2 (NP_003298.1).
性能
純化方法
Affinity purification
類型
Polyclonal Antibody
同種型
IgG
儲存/保存方法
Store at -20℃. Avoid freeze / thaw cycles.
存儲溶液
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
靶標(biāo)
背景說明
Rabbit anti-TRPM2 Polyclonal Antibody The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known.
細(xì)胞定位
Membrane,Multi-pass membrane protein
UniProt
O94759
實驗結(jié)果圖
Immunofluorescence analysis of HeLa cell using TRPM2 antibody. Blue: DAPI for nuclear staining.