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15000105423
15000105423
詳細介紹
| 品牌 | absin | 規格 | 10ug |
|---|---|---|---|
| 供貨周期 | 一周 |
| 概述 | |
|---|---|
| 描述 | Recombinant Human Tryptase beta-2 is produced by our Mammalian expression system and the target gene encoding Ala19-Pro275 is expressed with a 6His tag at the C-terminus. |
| 別名 | Tryptase Beta-2, Tryptase-2, Tryptase II, TPSB2, TPS2 |
| 形態 | Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. |
| 來源 | Human Cells |
| 氨基酸序列 | APAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDL AALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASET FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKPVDH HHHHH |
| 內毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| Accession # | P20231 |
| 性能 | |
|---|---|
| 背景 | Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders. |
| 保存方法 | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| 純度 | Greater than 95% as determined by reducing SDS-PAGE. |
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